Purkinje cell antibody (yo)

This is an important test that is used to diagnose rare forms of breast and gynecologic cancers.

Venous blood
1 tests included
7 days turnaround



About Purkinje cell antibody (yo)

What are Purkinje cells?

Purkinje cells are a type of neuron in the cerebellum. They are the largest type of neuron in the human brain and play essential roles in motor control and learning.

Antibodies to Purkinje cells (anti-Yo) are antibodies which attack the Purkinje cells of the cerebellum, leading to paraneoplastic cerebellar degeneration (PCD). Anti-Yo antibodies are associated with rare breast and gynecologic cancers which present with PCD, sometimes prior to symptoms of cancer.

In these cases prognosis relies heavily on early diagnosis and removal of tumours, as there is no effective treatment to reverse the condition.  

Why take the test?

This test screens for anti-Yo antibodies which target Purkinje cells in the cerebellum. It is used to diagnose rare forms of breast and gynecologic cancers which result in paraneoplastic cerebellar degeneration.


What's tested

Purkinje Cell Antibody (Yo)

How it works



Purchase your Kit

Just order a test online and get your kit delivered right to your door unless you are ordering a COVID-19 Fit to Fly test where you will be given appointment options to attend our clinics across the United Kingdom for a nose and throat swab PCR test at the checkout stage.



Take your test and post

Follow our simple instructions to take your sample and post back the enclosed prepaid envelope to our accredited lab for processing. We also offer home or workplace visits by a qualified nurse. For COVID-19 Fit to Fly tests you must attend one of our partner clinics for our trained collection officers to take your sample. You will then have the results emailed to you.



Get results directly to your dashboard

You will receive an email notification from our medical team when your results are available on your secure personalised health dashboard.