About Vitamin d (1-25 dihydroxy)
What is vitamin D?
Vitamin D is a fat-soluble vitamin with an important role in aiding the absorption of calcium, magnesium and phosphates. It also contributes to bone and musculoskeletal health. Vitamin D in the blood can be measured in two different forms; 1,25-dihydroxy vitamin D (1,25-OH) and 25-hydroxy vitamin D (25-OH). 25-OH vitamin D is generally inactive, circulating in the blood until it is converted to the active 1,25-OH vitamin D when required. 25-OH vitamin D is typically the preferred measure of vitamin D in the blood as it is present for longer and in higher concentrations than 1,25-OH vitamin D. Measuring 1,25-OH vitamin D is useful for monitoring conversion between 25-OH vitamin D and 1,25-OH vitamin D by the kidneys. In the UK, the sun is only powerful enough to stimulate vitamin D production in the skin between around April and September. Due to the fact that this is the primary source of vitamin D in the body, it is common for vitamin D deficiency to occur in many parts of the UK during the winter months without supplements. Problems converting 25-OH to 1,25-OH vitamin D can result in symptoms of vitamin D deficiency when there is adequate intake and production of vitamin D. Vitamin D deficiency can result in weakness in bones and muscles and has been associated with asthma in children and cognitive impairment in adults. Excess vitamin D through supplementation can lead to hypercalcemia.
Why take the test?
This test measures the levels of 1,25-OH vitamin D in the blood. It is typically used to diagnose disorders affecting the conversion of 25-OH to 1,25-OH vitamin D.
How it works
Order your kit
Just order a test online and get your kit delivered right to you door. Your kit contains everything you need for the test.
Take your test and post
Follow our simple instructions to take your sample and post back the enclosed prepaid envelope to our accredited lab for processing. We also offer home or workplace visits by a qualified nurse.
Get results directly to your dashboard
You will receive an email notification from our medical team when your results are available on your secure personalised health dashboard.
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